The Astros and Angels engaged in a pitching duel, with the Astros power winning the day 3-1. Shohei Ohtani invoked the pitcher-DH rule as he started on the mound and led off for the Angles. LAnaheim put their three best hitters at the top of the order, but the Astros limited Ohtani, Mike Trout, and Anthony Rendon to a single and a walk.

Ohtani pitched better than he hit, striking out nine and walking one, but did allow a run in 4 2/3 innings.

The Astros made the most of their eight hits, as six of them went for extra-bases. They needed solo home runs by Alex Bregman and Yordan Alvarez to win however, as the pair went back-to-back in the eighth inning to seal the victory. Framber Valdez pitched 6 2/3 shutout innings for the win, walking one and striking out six.

To the east in Arizona, the Diamondbacks take their home opener over the Padres 4-2 in an exciting finish. Yu Darvish and the San Diego bullpen stymied the Diamondbacks for eight innings, taking a 2-0 lead to the bottom of the ninth. Darvish did not allow a hit in his six innings of work.

When it came to the save situation in the ninth inning, new manager Bob Melvin called on Robert Suarez to make his major league debut. A veteran of Mexican and Japanese leagues, the seasonal age 31 pitcher came in to face Christian Walker. He walked in what turned out to be an inning for aptly named hitters. Suarez walked the next batter and hit the third, bringing in Craig Stammen to pitch with the bases loaded. He uncorked a wild pitch with Seth Beer batting on National Beer day. With the score 2-1, Beer crafted a home run, and the Diamondbacks walked off to know doubt have some brews.